Q:

The drug Clarinex is used to treat symptoms from allergies. In a clinical trial of this drug, 2% of the 1650 treated subjects experienced fatigue. Among the 1600 subjects given placebos, 1% experienced fatigue. Use a .05 significance level to test the claim that the incidence of fatigue is greater among those who use Clarinex.

Accepted Solution

A:
Answer:Claim is False that the incidence of fatigue is greater among those who use Clarinex.Step-by-step explanation:Let [tex]p_1[/tex] and [tex]p_2[/tex] be the probabilities of the the incidence of fatigue of those using Clarinex. and placebos respectively2% of the 1650 treated subjects experienced fatigue who are using Drug Clarinex.[tex]n_1[/tex] = 1650[tex]\widehat{p_1}=0.02[/tex] [tex]y_1=2\% \times 1650 =33[/tex]Among the 1600 subjects given placebos, 1% experienced fatigue.[tex]n_2[/tex] = 1600[tex]\widehat{p_2}=0.01[/tex] [tex]y_21\% \times 1600 =16[/tex]Claim : The incidence of fatigue is greater among those who use Clarinex.[tex]H_0:p_1\leq p_2\\H_a:p_1>p_2[/tex]We will use Comparing Two Proportions[tex]\widehat{p}=\frac{y_1+y_2}{n_1+n_2} =\frac{33+16}{1600+1650}=0.015[/tex]Formula of test statistic :[tex]\frac{\widehat{p_1}-\widehat{p_2}}{\sqrt{\widehat{p}(1-\widehat{p})(\frac{1}{n_1}+\frac{1}{n_2})}}[/tex]Substitute the values  test statistic :[tex]\frac{0.02-0.01}{\sqrt{0.015(1-0.015)(\frac{1}{1650}+\frac{1}{1600})}}[/tex] test statistic :2.344refer z table for p value  p value = 0.9904α = 0.05Since p value >αSo, we accept the null hypothesisSo, the claim is wrong that the incidence of fatigue is greater among those who use Clarinex.